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Mutations in UBA3 Confer Resistance to the NEDD8-Activating Enzyme  Inhibitor MLN4924 in Human Leukemic Cells
Mutations in UBA3 Confer Resistance to the NEDD8-Activating Enzyme Inhibitor MLN4924 in Human Leukemic Cells

Malvika Sharan on Twitter: "These 2 talks were public seminars at  @NCBS_Bangalore. It's inspiring to see how Hari and Norman share their  Scientific enthusiasm and contribute to each other's research in disorder
Malvika Sharan on Twitter: "These 2 talks were public seminars at @NCBS_Bangalore. It's inspiring to see how Hari and Norman share their Scientific enthusiasm and contribute to each other's research in disorder

Facility - Sirano Dhe Paganon, PhD - Structural & Chemical Biology Center
Facility - Sirano Dhe Paganon, PhD - Structural & Chemical Biology Center

PDF) Crystal Structure of the Pleckstrin Homology-Phosphotyrosine Binding  (PH-PTB) Targeting Region of Insulin Receptor Substrate 1
PDF) Crystal Structure of the Pleckstrin Homology-Phosphotyrosine Binding (PH-PTB) Targeting Region of Insulin Receptor Substrate 1

Covalent Modifiers: March 2020
Covalent Modifiers: March 2020

Sirano DHE-PAGANON | Dana-Farber Cancer Institute, Boston | DFCI |  Department of Cancer Biology
Sirano DHE-PAGANON | Dana-Farber Cancer Institute, Boston | DFCI | Department of Cancer Biology

Sirano DHE-PAGANON | Dana-Farber Cancer Institute, Boston | DFCI |  Department of Cancer Biology
Sirano DHE-PAGANON | Dana-Farber Cancer Institute, Boston | DFCI | Department of Cancer Biology

Loss of heterozygosity of essential genes represents a widespread class of  potential cancer vulnerabilities | Nature Communications
Loss of heterozygosity of essential genes represents a widespread class of potential cancer vulnerabilities | Nature Communications

Gunning Group | Collaborators
Gunning Group | Collaborators

Sirano Dhe-Paganon - Director and Principal Scientist, Longwood Center for  Structural & Chemical Biology - Dana-Farber Cancer Institute | LinkedIn
Sirano Dhe-Paganon - Director and Principal Scientist, Longwood Center for Structural & Chemical Biology - Dana-Farber Cancer Institute | LinkedIn

Facility - Sirano Dhe Paganon, PhD - Structural & Chemical Biology Center
Facility - Sirano Dhe Paganon, PhD - Structural & Chemical Biology Center

Leveraging Gas-Phase Fragmentation Pathways for Improved Identification and  Selective Detection of Targets Modified by Covalent Probes,Analytical  Chemistry - X-MOL
Leveraging Gas-Phase Fragmentation Pathways for Improved Identification and Selective Detection of Targets Modified by Covalent Probes,Analytical Chemistry - X-MOL

Selective USP7 inhibition elicits cancer cell killing through a  p53-dependent mechanism | Scientific Reports
Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism | Scientific Reports

Sirano Dhe Paganon, PhD - Structural & Chemical Biology Center - HOME
Sirano Dhe Paganon, PhD - Structural & Chemical Biology Center - HOME

Sirano DHE-PAGANON | Dana-Farber Cancer Institute, Boston | DFCI |  Department of Cancer Biology
Sirano DHE-PAGANON | Dana-Farber Cancer Institute, Boston | DFCI | Department of Cancer Biology

Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands -  Remillard - 2017 - Angewandte Chemie International Edition - Wiley Online  Library
Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands - Remillard - 2017 - Angewandte Chemie International Edition - Wiley Online Library

New chemical technology boosts potency of targeted cancer therapy -  Dana-Farber Cancer Institute | Boston, MA
New chemical technology boosts potency of targeted cancer therapy - Dana-Farber Cancer Institute | Boston, MA

PDF) FKBP Family Proteins: Immunophilins with Versatile Biological Functions
PDF) FKBP Family Proteins: Immunophilins with Versatile Biological Functions

New chemical technology boosts potency of targeted cancer therapy -  Dana-Farber Cancer Institute | Boston, MA
New chemical technology boosts potency of targeted cancer therapy - Dana-Farber Cancer Institute | Boston, MA

Phthalimide conjugation as a strategy for in vivo target protein degradation
Phthalimide conjugation as a strategy for in vivo target protein degradation

Core Facilities - Dana-Farber Cancer Institute | Boston, MA
Core Facilities - Dana-Farber Cancer Institute | Boston, MA

Facility - Sirano Dhe Paganon, PhD - Structural & Chemical Biology Center
Facility - Sirano Dhe Paganon, PhD - Structural & Chemical Biology Center

Figure - Nature Structural & Molecular Biology
Figure - Nature Structural & Molecular Biology

Sirano Dhe-Paganon's research works | Brandeis University, Waltham and  other places
Sirano Dhe-Paganon's research works | Brandeis University, Waltham and other places

Facility - Sirano Dhe Paganon, PhD - Structural & Chemical Biology Center
Facility - Sirano Dhe Paganon, PhD - Structural & Chemical Biology Center

Publications - Sirano Dhe Paganon, PhD - Structural & Chemical Biology  Center
Publications - Sirano Dhe Paganon, PhD - Structural & Chemical Biology Center